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Absence of menstruation (amenorrhea)
Absence of menstruation (amenorrhea)
Primary amenorrhea
Primary amenorrhea
Secondary amenorrhea
Secondary amenorrhea

Overview Symptoms Treatment Prevention

Menstruation - Absent   (Spanish Version)  

Definition:

Absent menstruation means no menstrual flow, or period. Absent menstruation may be:

  • Primary -- no menstruation before age 16
  • Secondary -- menstruation begins at the appropriate age, but later stops for more than 3 cycles or 6 months

Absent menstruation is called amenorrhea.



Alternative Names:

Missed periods; Lack of menses; Periods - missed; Amenorrhea



Considerations:

Many perfectly healthy females begin to menstruate later than most (the average age is about 13).

Pregnancy is often the first thought when a period is missed, but there are many reasons for having a late period. The rate of primary amenorrhea in the United States is less than 1%. The rate of secondary amenorrhea (due to some cause other than pregnancy) is about 4% in the general population.

Symptoms associated with amenorrhea depend on the cause and may include:



Common Causes:

Causes of primary amenorrhea:

  • Delay may be normal if puberty characteristics, such as breast development, are present by age 13
  • Birth defects of the female reproductive system
  • Lack of an opening in the membrane at the entrance of the vagina (hymen)
  • Problem with the hypothalamus or pituitary gland

Factors that can disrupt normal menstruation include:

Causes of secondary amenorrhea:

  • Pregnancy
  • Stress and anxiety
  • Drastic weight reduction
  • Significant weight gain or obesity
  • Hormonal imbalance (such as with polycystic ovarian syndrome)
  • Endocrine disorders such as thyroid disease or pituitary disease/tumor
  • IUD use
  • Too much exercise
  • Premature ovarian failure
  • Menopause (normal for women over age 45)
  • Use of birth control pills and other contraceptives
  • Uterine scarring, usually from procedures such as dilation and curettage (D and C)


References:

Master-Hunter T, Heiman DL. Amenorrhea: evaluation and treatment. Am Fam Physician. 2006;73:1374-1382.




Review Date: 6/26/2008
Reviewed By: Susan Storck, MD, FACOG, Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine; Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.


The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2003 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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