Lobar intracerebral hemorrhage is bleeding in the largest part of the brain called the cerebrum.

Hemorrhage - intraparenchymal; Hemorrhage - intracerebral (lobar)

Lobar intracerebral hemorrhage (ICH) may be caused by:

• Angioma, a type of blood vessel tumor
• Bleeding into a tumor
• Blood clotting problems
• Blood vessel problems such as aneurysm or arteriovenous malformation
• Head injury (trauma)

In some cases, no cause can be found.

When it is not caused by trauma, lobar ICH is considered a type of hemorrhagic stroke, the most serious type of stroke.

Lobar ICH is associated with the apolipoprotein (apo) E gene, which is linked to an increased risk for Alzheimer's disease.

Lobar hemorrhages are also associated with the following:

• Cerebral amyloid

  • Decreased levels of blood platelets
  • High blood pressure
  • Liver disease (associated with increased bleeding risk)
  • Some autoimmune disorders
• Use of aspirin or blood thinners
• Various blood or bleeding disorders such as disseminated intravascular coagulation, hemophilia, sickle cell anemia, and leukemia

Zivin JA. Hemorrhagic cerebrovascular disease. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 432.

Goldstein LB. Prevention and management of stroke. In: Libby P, Bonow RO, Mann DL, Zipes DP, eds. Libby: Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Saunders;2007:chap 58.