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Testicular Failure   (Spanish Version)  

Definition:

Testicular failure is the inability of the testicles to produce sperm or male hormones.

See also:



Alternative Names:

Primary hypogonadism - male



Causes, incidence, and risk factors:

Testicular failure is uncommon. Causes include:

  • Certain drugs, including glucocorticoids, ketoconazole, and opioids
  • Chromosome problems
  • Diseases that affect the testicle, including mumps, orchitis, and testicular cancer
  • Injury to the testicles

The following things increase the risk for testicular failure:



References:

Bhasin S. Testicular disorders. In: Kronenberg HM, Shlomo M, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 18.

Bhasin S, Cunningham GR, Hayes FJ, et al. Testosterone therapy in adult men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2006 Jun;91(6):1995-2010.




Review Date: 6/22/2009
Reviewed By: Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Louis S. Liou, MD, PhD, Assistant Professor of Urology, Department of Surgery, Boston University School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.


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